TzymeTM is the trademark of a proprietary blend of highly active, functional enzymes. These enzymes are pH balanced and GI tract stable. This blend is formulated to enhance the digestive process and impart systemic benefits.
The value of the "friendly bacteria" normally found in the human digestive tract, such as L. plantarum, L. acidophilus, L. casei, L. salivarius, L. sporogenes, and B. longum is well established.
L. plantarum is actually used as protective cultures to improve microbial safety of foods. This usage comes from their secretion of "bacteriocins" which are proteins that are lethal to certain other bacteria. L. plantarum has also been found in animal models to inhibit the translocation of bacteria from the gut to other organs (e.g., liver, lymph nodes).
Oral supplementation with L. acidophilus can enhance anti-infective mechanisms of defense. Research has suggested that one mechanism for the beneficial effects of swallowing L. acidophilus is stimulation of the production of interleukin-1 alpha and tumor necrosis factor-alpha. These substances have potent cytocidal and cytostatic effects on tumor cells.
The mechanisms of immune support by B. longum have been widely studied in animal models. It has been found that B. longum stimulates the immune system by enhancing the activity of natural killer cells in the spleen of rats and by stimulating intestinal IgA production.
L. casei has been demonstrated to have an immunostimulatory effect in human subjects. These beneficial bacteria promote the immunological barrier of the gut by the intestinal secretion of IgA.
L. sporogenes is a very resilient organism. It can sustain various conditions of the GI tract and helps to control pathogenic organisms. This bacteria is readily activated by the gastric acid and migrates down the GI tract where it produces lactic acid and various bacteriocins.
L. salivarius is a very resilient and highly prolific bacteria. Its actions reduce the production of toxic amines. These organisms produce highly active proteolytic enzymes that enhance hydrolysis of proteinaceous compounds in the colon.
TPPTM Probiotic also contains lactoferrin, which is currently the object of considerable study. Lactoferrin has been shown to be an effective antibacterial agent. It is even found in tears and serves as one component of the defense of the outer eye. Supplementation with lactoferrin has been found to inhibit bacterial translocation (from the digestive tract to other organs and systems), probably due to its suppression of bacterial overgrowth.
Jerusalem Artichoke is rich in inulin which is a polymer of fructose, also called fructooligosaccharides (FOS). FOS have been shown to serve as effective nutrients for intestinal probiotic bacteria (such an activity is sometimes call 'prebiotic'). Normal human digestive enzymes are unable to digest FOS. It therefore passes in its whole state into the colon where it becomes available as a nutrient to "friendly" bacteria."